Chemokine Receptors as Drug Targets, Volume 46 (Methods and by Martine J. Smit,Sergio A. Lira,Rob Leurs

By Martine J. Smit,Sergio A. Lira,Rob Leurs

Chemokines are hormone-like signaling molecules secreted via cells to sign an infection and consultant the immune reaction. Following a decade of easy chemokine study, the pharmaceutical has now all started to use this important signaling pathway for the improvement of cutting edge medicines opposed to AIDS, melanoma, neural and autoimmune illnesses. this is the 1st reference concentrating on those novel drug improvement opportunities.
establishing with a common advent on chemokine functionality and chemokine receptor biology, the second one half covers the identified implications of those signaling molecules in human ailments, reminiscent of melanoma, neural problems, and viral an infection, together with AIDS. The 3rd half systematically surveys present drug improvement efforts at concentrating on person chemokine receptors, in addition to different chemokine interplay companions, together with up to date stories from the pharmaceutical industry.

Show description

Read or Download Chemokine Receptors as Drug Targets, Volume 46 (Methods and Principles in Medicinal Chemistry) PDF

Best pharmacology books

Oral Lipid-Based Formulations: Enhancing the Bioavailability of Poorly Water-Soluble Drugs (Drugs and the Pharmaceutical Sciences)

Oral lipid-based formulations are attracting significant cognizance because of their ability to facilitate gastrointestinal absorption and decrease or do away with the influence of meals at the absorption of poorly water-soluble, lipophilic medicinal drugs. regardless of the most obvious and tested application of those formulations for addressing a chronic and becoming challenge of significant importance, the pharmaceutical has been gradual to use and extra increase this expertise.

Mucosal Delivery of Biopharmaceuticals: Biology, Challenges and Strategies

Biopharmaceutical medications, the latest type of therapeutics, are particularly heterogeneous and comprise a variety of molecules reminiscent of proteins, peptides, vaccines and nucleic acids, with use in almost all healing fields (e. g. melanoma and infectious illnesses, vaccination, metabolic dysfunctions) and diagnostics.

Pharmacological Basis of Acute Care

This publication is the 4th in a chain of Acute Care books written with the purpose to handle the wishes of wellbeing and fitness care companies whilst dealing with the acutely unwell sufferers. Globally it has develop into obvious that the research of pharmacology and next medical education has no longer regularly competently built younger medical professionals having the ability to administer medicines to their sufferers effectively and with a bit of luck, relatively within the severely ailing sufferer.

Bioinspired and Biomimetic Polymer Systems for Drug and Gene Delivery

The following, front-line researchers within the booming box of nanobiotechnology describe the main promising ways for bioinspired drug supply, encompassing small molecule supply, supply of healing proteins and gene supply. The providers surveyed comprise polymeric, proteinaceous and lipid structures at the nanoscale, with a spotlight on their adaptability for various cargoes and objective tissues.

Extra resources for Chemokine Receptors as Drug Targets, Volume 46 (Methods and Principles in Medicinal Chemistry)

Example text

Download PDF sample

Rated 4.39 of 5 – based on 42 votes