Biopharmaceutics Modeling and Simulations: Theory, Practice, by Kiyohiko Sugano

By Kiyohiko Sugano

A entire advent to utilizing modeling and simulation courses in drug discovery and development

Biopharmaceutical modeling has develop into imperative to the layout and improvement of recent medicinal drugs. Influencing key points of the advance approach, together with drug substance layout, formula layout, and toxicological publicity evaluation, biopharmaceutical modeling is now noticeable because the linchpin to a drug's destiny good fortune. And whereas there are various commercially to be had software program courses for drug modeling, there has no longer been a unmarried source guiding pharmaceutical pros to the particular instruments and practices had to layout and try secure drugs.

A advisor to the fundamentals of modeling and simulation courses, Biopharmaceutics Modeling and Simulations deals pharmaceutical scientists the keys to knowing how they paintings and are utilized in developing medications with wanted medicinal homes. starting with a spotlight at the oral absorption of gear, the e-book discusses:

  • The relevant dogma of oral drug absorption (the interaction of dissolution, solubility, and permeability of a drug), which varieties the foundation of the biopharmaceutical class procedure (BCS)
  • The thought of drug concentration
  • How to simulate key drug absorption processes
  • The physiological and drug estate info used for biopharmaceutical modeling
  • Reliable practices for reporting results

With over two hundred figures and illustrations and a peerless exam of the entire key points of drug research—including operating and reading types, validation, and compound and formula selection—this reference seamlessly brings jointly the confirmed useful techniques necessary to constructing the secure and powerful medications of tomorrow.

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