Aspartic Acid Proteases as Therapeutic Targets, Volume 45 by Arun K. Ghosh

By Arun K. Ghosh

during this ground-breaking sensible reference, the relatives of aspartic acid proteases is defined from a drug developer's viewpoint. the 1st half presents a basic creation to the relatives of aspartic acid proteases, their physiological capabilities, molecular constitution and inhibition. elements to 5 current quite a few case stories of profitable protease inhibitor drug layout and improvement, in addition to present and strength makes use of of such inhibitors in pharmaceutical drugs, masking the most important healing ambitions HIV-1 protease, renin, beta-secretase, gamma-secretase,plasmepsins and fungal proteases.
A prepared reference aimed essentially at execs within the pharmaceutical undefined, in addition to for an individual learning proteases and their function.

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